It still feels way too sensitive for me to hit things with the wire-guided missile, but I'll figure it out eventually. (Note that there's no actual indication that they're wire-guided, but it sure as hell isn't computer-guided).
I can maybe hit 33% of my targets, and at least cause splash damage or pilots to shit their pants with 100% of them. So I'm close!
I've finally started to hit targets accurately. I have to turn down my mouse sensitivity really really low though, and that lets me adjust things easier. Key is to get the missile lined up ASAP since it keeps speeding up as it goes, and the faster it's going, the harder to aim. Right at the beginning, do all the adjustments necessary, and you'll see improvements.
I typically get it aimed nicely at first, but the tricky part is keeping it still, or continuously adjusting for a moving target. I suppose you can just adjust early and have it lead your target (so it flies straight into it) instead of correcting it.
But yeah, generally it's going to require experience, or owning a mouse that changes its sensitivity on the fly.