Sounds like Adult Stem Cell Research did the trick. I didn't see anything in the article talking about using Embyros? Did I miss it?1 - Early stage retinal cells are taken from a newborn mouse
2 - They are transplanted into the retina of a mouse which has lost its sight
3 - The cells implant and connect with existing cells in the eye, restoring some sight to the mouse.
Last edited by Harmor (2006-11-08 10:37:02)
I'm confused...is this Adult Stem cells or Embyronic Stem cell?SpaceApollyon wrote:
"To get human retinal cells at the same stage of development, however, would involve taking stem cells from a foetus during the second trimester of pregnancy"
If the cells are from a three to five-day-old mouse then its 'Adult Stem Cell', right?The team took cells from three to five-day-old mice, a stage when the retina is about to be formed.
It's not ASCR, it's to do with differing stages of development in mice compared to humans. When mice are born their eyes are not properly developed, like dogs.Harmor wrote:
"They were able to help them see again by transplanting immature retinal stem cells into their eyes.'...Sounds like Adult Stem Cell Research did the trick. I didn't see anything in the article talking about using Embyros? Did I miss it?1 - Early stage retinal cells are taken from a newborn mouse
2 - They are transplanted into the retina of a mouse which has lost its sight
3 - The cells implant and connect with existing cells in the eye, restoring some sight to the mouse.
+1 And sorry MJF is wrong, Ironchef. Embryonic is crap, compared to the accomlishments of ASCR, but there's already 2 lengthy threads about this subject. Let's go read those instead of rehashing it here.Harmor wrote:
"They were able to help them see again by transplanting immature retinal stem cells into their eyes.'...Sounds like Adult Stem Cell Research did the trick. I didn't see anything in the article talking about using Embyros? Did I miss it?1 - Early stage retinal cells are taken from a newborn mouse
2 - They are transplanted into the retina of a mouse which has lost its sight
3 - The cells implant and connect with existing cells in the eye, restoring some sight to the mouse.
You call making blind mice see, crap? It's much better than anything accomplished by ASCR. ASCR has it's place, but the developments it produces are not as dramatic as ESCR. The results from ASCR do tend to be more immediately practical, but they do not have such great potential.Stingray24 wrote:
+1 And sorry MJF is wrong, Ironchef. Embryonic is crap, compared to the accomlishments of ASCR, but there's already 2 lengthy threads about this subject. Let's go read those instead of rehashing it here.Harmor wrote:
"They were able to help them see again by transplanting immature retinal stem cells into their eyes.'...Sounds like Adult Stem Cell Research did the trick. I didn't see anything in the article talking about using Embyros? Did I miss it?1 - Early stage retinal cells are taken from a newborn mouse
2 - They are transplanted into the retina of a mouse which has lost its sight
3 - The cells implant and connect with existing cells in the eye, restoring some sight to the mouse.
Adult stem cells are the future, I don't know why you guys are clinging to the past.The Article wrote:
To get human retinal cells at the same stage of development, however, would involve taking stem cells from a foetus during the second trimester of pregnancy.
But Dr Robert MacLaren, a specialist at Moorfields Eye Hospital who worked on the research, said they did not want to go down that route.
He said the aim now would be to look at adult stem cells to see if they could be genetically altered to behave like the mouse retinal cells.
Nevertheless, they have successfully treated the mice with embryonic stem cells. Adult stem cells were not used. Your quote is just pointing out that they would rather use adult stem cells in future. There is no guarantee that will work though.AlbertWesker[RE] wrote:
Try reading the WHOLE article next time:Adult stem cells are the future, I don't know why you guys are clinging to the past.The Article wrote:
To get human retinal cells at the same stage of development, however, would involve taking stem cells from a foetus during the second trimester of pregnancy.
But Dr Robert MacLaren, a specialist at Moorfields Eye Hospital who worked on the research, said they did not want to go down that route.
He said the aim now would be to look at adult stem cells to see if they could be genetically altered to behave like the mouse retinal cells.
Number of treatments from Adult stem cells: 156.
Number of treatments from embryonic stem cells: 0
Last edited by Bertster7 (2006-11-08 11:18:24)
I have already been over this. It is to do with the differences in stages of development between mice and humans. When a human is born their eyes are already developed and work. Mice, like dogs, are born blind - their eyes develop later. In the article it says the stages of development of the cells used is equivalent to embryonic stem cells in humans.Harmor wrote:
Are we reading the same article...PLEASE someone explain to me where in the article is shows that it was embryoics stem cells? The cells were from three to five-day-old mice, which means to me that its 'Adult Stem Cells'.
Someone correct me if I'm wrong.
They also mention they would prefer to take the adult stem cell route in humans, but they don't know if that will work.BBC wrote:
To get human retinal cells at the same stage of development, however, would involve taking stem cells from a foetus during the second trimester of pregnancy
Checkmate.AlbertWesker[RE] wrote:
Try reading the WHOLE article next time:Adult stem cells are the future, I don't know why you guys are clinging to the past.The Article wrote:
To get human retinal cells at the same stage of development, however, would involve taking stem cells from a foetus during the second trimester of pregnancy.
But Dr Robert MacLaren, a specialist at Moorfields Eye Hospital who worked on the research, said they did not want to go down that route.
He said the aim now would be to look at adult stem cells to see if they could be genetically altered to behave like the mouse retinal cells.
Number of treatments from Adult stem cells: 156.
Number of treatments from embryonic stem cells: 0
Yay, they're still mouse cells, not human cells. As AlbertWesker[RE] pointed out, zippo treatments from human embroynic cells.Bertster7 wrote:
. . . In the article it says the stages of development of the cells used is equivalent to embryonic stem cells in humans.
What are you talking about. No one said anything about using children as ginuea pigs.Jenkinsbball wrote:
Having a baby on the way now, it puts stem cell research into a new light for me. Although I would never do it, I can't see how a mother would let her child be used as a fucking ginuea pig like that...
So? As I have continually said, ES research is all about the potential for the cells. It is research for the long term, which is why there is so little interest in private funding for it. ASCR is a much more practical research area for the near future, with many practical treatments already underway.Stingray24 wrote:
Yay, they're still mouse cells, not human cells. As AlbertWesker[RE] pointed out, zippo treatments from human embroynic cells.Bertster7 wrote:
. . . In the article it says the stages of development of the cells used is equivalent to embryonic stem cells in humans.
Last edited by Bertster7 (2006-11-08 13:44:57)
Moooooo.Bertster7 wrote:
So? As I have continually said, ES research is all about the potential for the cells. It is research for the long term, which is why there is so little interest in private funding for it. ASCR is a much more practical research area for the near future, with many practical treatments already underway.Stingray24 wrote:
Yay, they're still mouse cells, not human cells. As AlbertWesker[RE] pointed out, zippo treatments from human embroynic cells.Bertster7 wrote:
. . . In the article it says the stages of development of the cells used is equivalent to embryonic stem cells in humans.
Another recent development in ESCR is the development of hybrid Cow ES cells. Cow eggs are combined with human DNA to produce cells that can be grown without the need for human foetuses to be involved (unlike Lanza's idea, this actually works). This practice has also been condemned by religious groups. A lot like vaccination was, it was thought (by religious types at least) that using the strain of smallpox from cows as a vaccine would cause a person to exhibit bestial tendancies. It did not, obviously, and vaccines now save millions of lives.
Last edited by Agent_Dung_Bomb (2006-11-08 13:35:09)
Exactly.Agent_Dung_Bomb wrote:
What are you talking about. No one said anything about using children as ginuea pigs.Jenkinsbball wrote:
Having a baby on the way now, it puts stem cell research into a new light for me. Although I would never do it, I can't see how a mother would let her child be used as a fucking ginuea pig like that...
If you think curing blindness is pointless....sfarrar33 wrote:
ah what a pointless thread
and ah what a pointless comment i make but hey...
no i see it as pointless to argue about it, its fairly obvious that most people are just randomly going on about the difference between ASCR and ESCR, but the point is?Bertster7 wrote:
If you think curing blindness is pointless....sfarrar33 wrote:
ah what a pointless thread
and ah what a pointless comment i make but hey...
Personally I see it as an important scientific breakthrough.
The point is that this is a radical new treatment using a new and unproven branch of science (ESCR) which despite it's controversy has extreme potential for curing the uncurable - like blindness.sfarrar33 wrote:
no i see it as pointless to argue about it, its fairly obvious that most people are just randomly going on about the difference between ASCR and ESCR, but the point is?Bertster7 wrote:
If you think curing blindness is pointless....sfarrar33 wrote:
ah what a pointless thread
and ah what a pointless comment i make but hey...
Personally I see it as an important scientific breakthrough.
Isn't it illegal to kill a fetus in the third-trimester? I mean the Surpreme Court is today discussing the legality of Partial Birth Abortion.Bertster7 wrote:
I have already been over this. It is to do with the differences in stages of development between mice and humans. When a human is born their eyes are already developed and work. Mice, like dogs, are born blind - their eyes develop later. In the article it says the stages of development of the cells used is equivalent to embryonic stem cells in humans.Harmor wrote:
Are we reading the same article...PLEASE someone explain to me where in the article is shows that it was embryoics stem cells? The cells were from three to five-day-old mice, which means to me that its 'Adult Stem Cells'.
Someone correct me if I'm wrong.They also mention they would prefer to take the adult stem cell route in humans, but they don't know if that will work.BBC wrote:
To get human retinal cells at the same stage of development, however, would involve taking stem cells from a foetus during the second trimester of pregnancy
Hope thats cleared it up for you a bit.
Last edited by Harmor (2006-11-08 15:22:01)