Larssen
Member
+99|2130
https://www.theguardian.com/australia-n … a-suggests

Australians may have to receive two or even three Covid jabs each year to maintain defences against the virus if early results on the efficacy of booster shots turn out to be a useful guide.

Weekly data published just before Christmas by the UK’s Health Security Agency shows the effectiveness of both the Pfizer and Moderna boosters against symptomatic diseases is lower for the Omicron than the Delta variant across all periods after the injection.

Health worker with Pfizer vaccine
Why has Australia reduced the Covid vaccine booster shot wait time to five months?
Read more
The analysis included 147,597 Delta and 68,489 Omicron cases in the UK. The agency stressed the “results should be interpreted with caution due to the low counts and the possible biases related to the populations with highest exposure to Omicron (including travellers and their close contacts) which cannot fully be accounted for”.

The UK data showed both Pfizer and Moderna boosters had 90% effectiveness against symptomatic diseases from the Delta variant up to at least nine weeks.

By contrast, efficacy against the Omicron strain was about 30% lower, and appeared to drop away further after nine weeks.

Last edited by Larssen (2022-01-01 12:48:01)

uziq
Member
+496|3694
(a) omicron is much weaker than delta, so the alarming news of their reduced efficacy is hardly 'bad' news'.

(b) moderna and pfizer are specifically working on a new formulation of their vaccine for omicron.

it's conceivable that we will have much better and much improved treatments as time goes on and covid establishes longer-term patterns and cycles.

why you need to trumpet every bit of bad news is bizarre to me. you've become every bit as doomer and hysterical as dilbert.

remind me, once again, how many people have died of omicron?

4.5 per cent of patients admitted to hospital died during the Omicron wave, compared with 21.3 per cent in a period before the new variant
... oh.

and can i remind you, once again, that even 60-70% effectivity against a coronavirus is very good by all vaccine measures.  if omicron is effectively as severe as a mild bout of flu for most people, why are you catastrophizing about an (old, soon-to-be-updated) vaccine being as effective as a flu vaccine is for flu? jesus christ, get some perspective.

i am really over the spectacle of people in first-world western nations moaning about the fact they have to get a (free, easily accessible, safe) booster shot every 4 or 5 months.

Last edited by uziq (2022-01-01 12:54:37)

Larssen
Member
+99|2130
Interesting twist to get pissed at the results from a study of the UK health security agency. Yeah surely I'm just beating a doomer drum. Get your head out your ass.

It is still too early to tell if omicron will seriously impact health services. The wave has just begun, yet you tout the results from preliminary studies as if they're definitive. Look at France's numbers. They have one of the best dashboards: https://www.gouvernement.fr/info-corona … et-donnees

You can see that delta started losing ground at about 14th of december. 50% of infections still appear to be delta at present. That's a potential shitstorm in itself. Regarding omicron, it's not positive news that the R is going up this dramatically and that efficacy of some vaccines, notably pfizer, drops to 30-40%.

If end of january comes and there hasn't been significant increase in hospitalisations & IC occupancy I'll agree that we might be alright here.

As for you 'being over' people moaning about having to get a booster every 5 months;

- data all over the world suggests significantly less people are getting a booster vs. the total initially vaccinated population. I expect that number to drop with each round of boosters. If people stop taking the vaccine in large numbers, and protection keeps dropping esp. for those who didn't even take 1 booster, that's another potential problem for the health services.

Last edited by Larssen (2022-01-01 13:12:19)

uziq
Member
+496|3694
it drops by 30% of its previous level, not 'it's only 30% effective'. pfizer was previously 90%+ effective. can you math?

nothing so far suggests that omicron is anywhere near as dangerous as delta. not a single country in the world is reporting a spike in serious illness and death and we are way past t+ 1 month after the strain's appearance. it isn't happening.

as i said before, hospital admissions numbers are way up but, as far as the omicron illness profile goes, it is a mild illness and people leave hospital on average after 2-3 days. this is also from the 'UK health security agency' as a source, so.

i said you're beating a doomer drum because you seem to relish the worst-case forecasts on this thing. that's been your tune for the last 6 months almost. you sound burnt out and depressed. the death rate has been basically flat since societies reached 80%+ vaccination.

you're right that we have a political and social battle ahead of us if we want to convince the science-denying retards what's good for them. but that doesn't mean i'm going to shit my pants over an article that says the obvious about omicron: namely that a highly mutated strain isn't covered as well by 1-year-old vaccines.
Larssen
Member
+99|2130
Among those who received
an AstraZeneca primary course, vaccine effectiveness was around 60% 2 to 4 weeks after
either a Pfizer or Moderna booster, then dropped to 35% with a Pfizer booster and 45% with
a Moderna booster by 10 weeks after the booster. Among those who received a Pfizer primary
course, vaccine effectiveness was around 70% after a Pfizer booster, dropping to 45% after 10+
weeks;
uziq
Member
+496|3694
so for people with 2x mRNA primaries, which have always been touted as the most effective for long-term effectivity, their protection is 45% after 3 months.

not quite the same as 'pfizer only gives you 30% protection', is it?

and, yet again, we are at this point using vaccines tooled for the first wave of covid against the fourth wave. they are ridiculously out of date. new ones are in development.

i would quite agree with you if these out-of-date vaccines were seeing a dramatic rise in deaths. but they're not. they're still holding for the vast majority of people and they are still buying us time until the revised versions come. so what's the big apocalypse?

90% of people in ICUs at this point are people who have never received a vaccine. i am really not concerned about the length of protection conferred by the booster shots. people who have been vaccinated recently are simply not getting sick and dying from omicron.

in every country that has been overwhelmed with an omicron wave, incidentally the levels of delta and antecedent strains drop off the map. south africa and the UK, for instance, now have very low incidences of delta. literally exactly what i predicted at the start of this wave, and which i was cussed out for by dilbert - "you're insane" - has happened. a much more successful variant in evolutionary terms has nudged off the heavyweights.
Cybargs
Moderated
+2,285|6959
yeh delta is basacially gone in aus. went from 200 a day in my state to now 20k a day infection with 20% positivity rate from testing... compared to at most 0.1% during OG rona or delta.
https://cache.www.gametracker.com/server_info/203.46.105.23:21300/b_350_20_692108_381007_FFFFFF_000000.png
Dilbert_X
The X stands for
+1,815|6348|eXtreme to the maX
For all of uziq's prattling about how everything is going great and Omicron is harmless the actual death rate is barely changing.

https://i.imgur.com/Bw7ljI0.png

We could still be in for a worse variant, but of course travel being so important - which is to say uziq wants to take a trip to Japan next - it will be allowed to rip through before we even know its happening.
Fuck Israel
SuperJail Warden
Gone Forever
+641|3962
Just give up trying to stop COVID. Take a trip to South America with some of your closest friend and have some funny tasting Kool-Aid together before the FBI comes to shut you down.
https://i.imgur.com/xsoGn9X.jpg
uziq
Member
+496|3694

Dilbert_X wrote:

For all of uziq's prattling about how everything is going great and Omicron is harmless the actual death rate is barely changing.

https://i.imgur.com/Bw7ljI0.png

We could still be in for a worse variant, but of course travel being so important - which is to say uziq wants to take a trip to Japan next - it will be allowed to rip through before we even know its happening.
erm, first of all, i have just said about 3 times in the last page that the death rate has remained basically flat since widespread vaccination has become more and more common. and secondly, on that global graph the case/death rates at this winter peak are basically half of last year's. so thanks for reinforcing my point, i guess ... ?

even the much nastier delta wave barely made a difference to highly vaccinated societies. a huge danger for the unvaccinated, certainly. but mass death and the potential for ICU meltdowns like in the early pre-vaccination waves? no. the vaccines work, for 'all of your prattling' to the contrary.

as for 'the death rate has barely changed', it is clearly coming down, week-on-week. something you conveniently ignored when i highlighted this to you from the UK data you waved in my face in your condescending, idiot way. delta is still highly prevalent in many countries and delta's death-rate by all current reckoning is 4-5x worse. so i would not expect it to change drastically in a short period whilst delta is still around to clusterbomb the unvaccinated, no.

going to japan next year will be nice. i'm obviously not going to go until they deem it safe, and japan have pretty consistently been the most conservative country on earth when it comes to opening their borders to tourists. i have no problem with that.

it's so funny that you want to make out all of my arguments are based in base self-interest. as if everything i've written here is because i want to go to japan. grow the fuck up dilbert. this is a very amusing way for you to divert away from the fact that i've basically been right about everything in this discussion for the last 3 months, and you've been an hysterical blow-bag flapping in the wind with inane talk about 'if only we had stopped china ...'.

go look at your posts again right about the time omicron surfaced. doom and gloom and constant shit-talking about the vaccines. turns out the vaccines cope perfectly well against serious illness for 3-4 months and that we have lots more promising medicine in the pipeline. go look at your replies to me again aroundabout the time this thing surfaced. i said to wait for data and that there's every chance its rapid spread could indirectly benefit us. you totally rubbished it as insane talk. and yet here we are. omicron could potentially even open a way out for us if it establishes itself as the dominant strain. then it really will join the host of 4-5 other major coronaviruses that spread endemically each year as 'the common cold'. wowsers!

Last edited by uziq (2022-01-02 02:08:30)

Dilbert_X
The X stands for
+1,815|6348|eXtreme to the maX
How does the rapid spread benefit us?

Apparently having delta gives little protection against Omicron, the next variant could easily defeat immunity from prior infections and vaccination and be more severe.

Letting covid rip is not sensible policy at all.
Fuck Israel
uziq
Member
+496|3694
We could still be in for a worse variant, but of course travel being so important
cross-border travel isn't what creates the risk of new variants appearing. it's free transmission between the unvaccinated. as it turns out, particularly amongst the immunocompromised unvaccinated (like in AIDS-torn southern africa).

this is an argument for vaccine equality, not for inane border restrictions. if corona is firestorming freely in unvaccinated countries in most of the global south, what fucking difference does it make that france have a 3 day quarantine on british arrivals?

use. your. fucking. thick. head.
Dilbert_X
The X stands for
+1,815|6348|eXtreme to the maX
Until we have vaccine equality border restrictions are a no-brainer.

Um I don't know, maybe the French don't want infections from the global south travelling in via Britain?

Speaking of the frogs, LMAO
https://www.politico.eu/article/eu-base … any-warns/
Fuck Israel
uziq
Member
+496|3694

Dilbert_X wrote:

Apparently having delta gives little protection against Omicron, the next variant could easily defeat immunity from prior infections and vaccination and be
the extremely low rate of hospitalizations and deaths in south africa was because people had high antibodies and robust immune systems to the new strain. want to know why? because corona has spread widely in south africa with each variant wave.

south africa is only 45% fully vaccinated.

reduced protection against omicron? certainly. 'little protection'? no.

the idea that covid will suddenly mutate into a whole new beast that will totally defeat vaccines and reset the pandemic is very fanciful at this stage. we have tracked hundreds, if not thousands, of variants. no major strain to appear and quickly assert evolutionary dominance has foiled our vaccines. once again, we are still posting seasonal flu levels of protection using 2 year old vaccines.
SuperJail Warden
Gone Forever
+641|3962
3 years into this and here I am still waiting for the strain that makes people eat other people.
https://i.imgur.com/xsoGn9X.jpg
uziq
Member
+496|3694

Dilbert_X wrote:

Until we have vaccine equality border restrictions are a no-brainer.

Um I don't know, maybe the French don't want infections from the global south travelling in via Britain?

Speaking of the frogs, LMAO
https://www.politico.eu/article/eu-base … any-warns/
i'd be a little more worried about the 30-40% of your domestic population who don't want a vaccine and who keep gathering to protest their right to be dangerous idiots, if i were you. a variant appearing there on your doorstep is a more much proximal risk to you than what happens in zulu-land.
Dilbert_X
The X stands for
+1,815|6348|eXtreme to the maX
30-40%? You're thinking of Israel

Aus is at 91.4% vaccination

Where on earth are you getting your information? A potato?
Fuck Israel
Dilbert_X
The X stands for
+1,815|6348|eXtreme to the maX

uziq wrote:

the idea that covid will suddenly mutate into a whole new beast that will totally defeat vaccines and reset the pandemic is very fanciful at this stage. we have tracked hundreds, if not thousands, of variants. no major strain to appear and quickly assert evolutionary dominance has foiled our vaccines. once again, we are still posting seasonal flu levels of protection using 2 year old vaccines.
Delta, variant 4?, was a nasty shock no?

Of course it can mutate into anything it likes.
Fuck Israel
uziq
Member
+496|3694

Dilbert_X wrote:

30-40%? You're thinking of Israel

Aus is at 91.4% vaccination

Where on earth are you getting your information? A potato?
i was generalizing about western nations like germany, france, UK, USA, australia, etc. you know, generally the ones who are instating these travel bans on the global south in a slap-happy fashion whilst also dealing with huge anti-vax protest movements within their own borders.

this may surprise you, but literally no one gives a fuck about a country of 20 million at the bottom of the world. i have never read a single in-depth news article about australia's covid experience. it's somewhere less interesting than ireland on my global consciousness. there are as many people within 10 square kilometres of where i'm sat right now in my neighbourhood, as there are in your entire blessed 'model state'.

Delta, variant 4?, was a nasty shock no?
only to the unvaccinated. recently vaccinated people had 90%+ protection against delta, too. i have cited these figures at you about 15 times and you still seem to want to ignore them. the vaccines we have really are/have been incredibly, fortuitously good. take your booster and stop worrying about new variants. and guess what? whilst you're not worrying, people are working on revised vaccines for the latest bevvy of variants. good stuff eh!

Of course it can mutate into anything it likes.
uhm, yes, ok sure dilbert. now you're just making up stuff. we are talking about science, not sci-fi. sars-cov-2 is a fairly simple microorganism and there are only so many moving 'parts' or RNA expressions that can mutate. it's not suddenly going to sprout tentacles or begin targeting your brain. you do know all the other coronaviruses we have been dealing with for perpetuity, aka 'the common cold', are also highly mutative too, right? that's why we've never devised cures for them. when's the last time you heard about HCoV-OC43 or HCoV-NL63 suddenly mutating one year into a killer common cold? oh yeah. they can quite literally not 'mutate into anything [they] like'.

Last edited by uziq (2022-01-02 01:59:03)

SuperJail Warden
Gone Forever
+641|3962
I have to go back to work tomorrow but not really. One week virtual my ass. If they didn't have the heart to stay open they won't have the heart to reopen. Cowards.
https://i.imgur.com/xsoGn9X.jpg
uziq
Member
+496|3694
https://www.theguardian.com/world/2022/ … mage-lungs

A growing body of evidence indicates that the Omicron Covid variant is more likely to infect the throat than the lungs, which scientists believe may explain why it appears to be more infectious but less deadly than other versions of the virus. Six studies – four published since Christmas Eve – have found that Omicron does not damage people’s lungs as much as the Delta and other previous variants of Covid. The studies have yet to be peer-reviewed by other scientists.

“The result of all the mutations that make Omicron different from previous variants is that it may have altered its ability to infect different sorts of cells,” said Deenan Pillay, professor of virology at University College London.

“In essence, it looks to be more able to infect the upper respiratory tract – cells in the throat. So it would multiply in cells there more readily than in cells deep in the lung. This is really preliminary but the studies point in the same direction.”

If the virus produces more cells in the throat, that makes it more transmissible, which would help to explain the rapid spread of Omicron. A virus that is good at infecting lung tissue, on the other hand, will be potentially more dangerous but less transmissible.
i've been reading these studies as they reach pre-print servers and this is almost very certainly what is happening. omicron is a sore throat, not a life-threatening disruption to your ability to get oxygen and a trip to ICU.

if omicron really is much more transmissible and much more successful at reproducing in our bodies than delta/alpha/etc, then this is surely a benison for our efforts. high levels of passive immunity and antibodies in a population thanks to high levels of omicron circulation will mean that other covid variants are greatly weakened and at a disadvantage.

we are not in control of this pandemic and, regardless of what dilbert says, it's pretty fanciful that we ever were and could be tbh. we have been along for a wild ride, able to control its pressure and rates of infection here and there, in a temporary and ad hoc way, but in the macro-scale being pretty much powerless to do anything. every variant to surface has made its way around the world regardless of our actions, stringent or relaxed. lockdowns and 'zero covid' policies have bought some societies time - valuable, life saving time, no doubt - before the inevitable leak or outbreak and then the house of cards coming down.

if we are unable to control the pandemic on a global scale, as surely is the case, the best we can do is hope to 'catch a wave' and take advantage of a variant like omicron. it really would be much better for the future if a version of covid adapted to the upper respiratory tract and throat became the predominant strain. that means no more long covid and fucked lungs, no more sudden oxygen dips in the middle of the night and no more wheeling out your 30 year old son on a stretcher.

Last edited by uziq (2022-01-02 02:56:56)

Dilbert_X
The X stands for
+1,815|6348|eXtreme to the maX

uziq wrote:

this may surprise you, but literally no one gives a fuck about a country of 20 million at the bottom of the world. i
Well maybe they should as our covid response has, up to now, been the one of best amongst first world nations.
Fuck Israel
uziq
Member
+496|3694
you’re a remote island of 20 million.

a much better example would be, say, a nation like korea. who never closed their borders.

in any case, australia started to slip and fail after delta, like all nations theretofore pursuing ‘zero-covid’ policies. omicron, being an order of magnitude more infectious, has certainly done for your policy of suppression. the point being that 250 days of lockdown and any number of other measures still didn’t produce the desired result. you were slowly losing your grip on the inevitable.

you’ve never been able to actually produce a coherent exit strategy for this australia model. city-wide lockdowns and closed borders, even to your own citizens, every time there’s a new wave or variant? or just permanently? what’s the measurable, defined goal or point at which you can pivot away from this? it’s not sustainable. especially considering the rest of the world, including more importantly your near-neighbours, are not in lockstep with your strategy.

judging from the rates of compliance, protests, rule breakers, etc, in your general population, it looks as if it was becoming unsustainable in the very near future, indeed. yes, 'people are stupid, iDiOcRacY', etc, etc, - yawn - but also people are not machines. people won't endure being asked to do nothing in their lives except risky work/WFH on a poorly defined/indefinite basis.

Last edited by uziq (2022-01-02 03:21:05)

Cybargs
Moderated
+2,285|6959

Dilbert_X wrote:

uziq wrote:

this may surprise you, but literally no one gives a fuck about a country of 20 million at the bottom of the world. i
Well maybe they should as our covid response has, up to now, been the one of best amongst first world nations.
taiwan #1.

island nations do have an innate advantage. somehow japan just didnt get hit with omnicron and delta "mutated itself to death" or something.
https://cache.www.gametracker.com/server_info/203.46.105.23:21300/b_350_20_692108_381007_FFFFFF_000000.png
Cybargs
Moderated
+2,285|6959

uziq wrote:

you’re a remote island of 20 million.

a much better example would be, say, a nation like korea. who never closed their borders.

in any case, australia started to slip and fail after delta, like all nations theretofore pursuing ‘zero-covid’ policies. omicron, being an order of magnitude more infectious, has certainly done for your policy of suppression. the point being that 250 days of lockdown and any number of other measures still didn’t produce the desired result. you were slowly losing your grip on the inevitable.

you’ve never been able to actually produce a coherent exit strategy for this australia model. city-wide lockdowns and closed borders, even to your own citizens, every time there’s a new wave or variant? or just permanently? what’s the measurable, defined goal or point at which you can pivot away from this? it’s not sustainable. especially considering the rest of the world, including more importantly your near-neighbours, are not in lockstep with your strategy.

judging from the rates of compliance, protests, rule breakers, etc, in your general population, it looks as if it was becoming unsustainable in the very near future, indeed. yes, 'people are stupid, iDiOcRacY', etc, etc, - yawn - but also people are not machines. people won't endure being asked to do nothing in their lives except risky work/WFH on a poorly defined/indefinite basis.
tbh there isn't a policy of supression anymore. NSW currently has a "LET IT RIP" premier and it's... ripping very well into the community. positivity rate is at 20% for testing and theyve basically given up. death rates still extremely low so that is nice.
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